WebJul 19, 2024 · Glucose oxidase (GOx) is an endogenous oxido-reductase that is widely distributed in living organisms. Over recent years, GOx has attracted increasing interest in the biomedical field due to its inherent biocompatibility, non-toxicity, and unique catalysis against β- D -glucose. WebFeb 1, 2024 · On the other hand, the hypoxia environment resulted from GOx-mediated oxygen consumption can also be well exploited, for the reason that increased hypoxia levels in the TME can activate hypoxia ...
A Glucose/Oxygen-Exhausting Nanoreactor for Starvation- and Hypoxia ...
WebA glucose oxidase (Gox)-based nanozyme system is safe and efficient to induce Fenton reactions in a quite specific and well-controlled way [19], and this nanozyme can oxidize … WebApr 11, 2024 · In order to clarify the antitumor mechanism of HFNP@GOX@PFC nanosystem, we first investigated hypoxia suppression in vivo, as the level of endogenous O 2 was close with GOX-mediated starvation effect, and the H 2 O 2 produced by GOX also affected the subsequent CDT and the overall antitumor effect. The IFC analysis of … artinya cc adalah
A smart nanoplatform for synergistic starvation, hypoxia …
Web1 day ago · Hypoxia increases patient treatment resistance and favors cancer progression. Nanozymes have received unprecedented attention in alleviating hypoxia v… WebGOx-Functionalized Platelet Membranes-Camouflaging Nanoreactors for Enhanced Multimodal Tumor Treatment . Fulltext; Metrics; Get Permission; Cite this article; Authors Du Y, Wang S, Luan J, Zhang M , Chen B, Shen Y. Received 11 February 2024. Accepted for publication 13 June 2024 WebFurthermore, by transferring H 2 O 2 to O 2, the GOx/CAT-NCs could be applied to spatiotemporally controlled cancer therapy by reducing tumor hypoxia. Therefore, cutting off the glucose metabolism of cancer cells by long-term starvation therapy and damaging intracellular components by powerful PDT was a highly efficient strategy for synergistic ... bandenmaat kia picanto 2016